What is Alzheimer's Disease?
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that results in the impairment of memory and intellectual capacity. While it is characterized by the loss of neurons and neuronal connections in select areas of the brain, pathological alterations and neuronal dysfunction appears to occur on a much larger scale. The neurodegenerative affects of AD are believed to be the result of deposits of certain proteins (amyloid, tau, and cerebrovascular amyloid), in and around neurons. The build-up of these proteins has been shown to interrupt cellular communication, function, structure, and metabolism. Because of the progressive nature of AD an individual’s quality of life is seriously limited and places a great burden on the responsible caregivers.
What are the Typical Symptoms/Complications of Alzheimer’s Disease?
Cognitive decline : difficulty thinking and understanding, confusion, delusion, forgetfulness.
Behavorial: aggression, agitation, difficulty with self care, irritability, wandering and getting lost.
Mood: Anger, apathy, general discontent, loneliness or mood swings
Psychological: depression, hallucination, paranoia
Loss of appetite or paranoia
What causes Alzheimer’s Disease?
Scientists aren’t sure why some people get Alzheimer’s disease and others do not. But they do know that the symptoms are caused by two different type of nerve damage:
· Nerve cell tangles in the brain called neurofibrillary tangles – these are twisted fibers found inside the brain’s cells. These tangles interfere with numerous cellular functions.
· Protein deposits called beta-amyloid plaques build up in the brain. This results in blocked cell-to-cell signaling at synapses. They may also activate immune system cells that trigger inflammation.
What type of stem cells are used and why?
TruStem Cell Therapy provides access to treatment that utilizes a patient’s stem cells isolated from their own bone marrow. There are multiple inherent benefits afforded by the utilization of bone marrow derived stem cells including their ability to differentiate into a broad variety of cells types (neurons, bone, cartilage, muscle, tendon, etc.), they are present at comparatively much higher levels than other stem cell types, possess unique immune-modulating properties, and they do not endanger a patient’s health the way other stem cells might.
What steps are involved in receiving treatment through TruStem Cell TherapyTM?
There are three steps involved:
First a blood draw is performed followed by a minimally invasive bone marrow harvest via the iliac crest. Approximately 100cc’s of a patient’s own bone marrow is harvested through a minimally invasive, bone marrow aspiration procedure. TruStem Cell Therapy utilizes a powered bone marrow access system combined with local anesthetic allowing for consistently larger specimen of cells, extremely low levels of pain/invasiveness reported by most patients, and higher levels of sterility.
Process + Activate
Both the blood and bone marrow are immediately delivered to our dedicated, onsite laboratory staffed by our team of technicians. Once your sample is in the lab our advanced proprietary process isolates and excites regenerative cells and concentrates healing factors to hyper-physiological levels in order to facilitate the creation of a highly effective, injectable therapeutic.
TruStem Cell Therapy utilizes both systematic and novel administration methods to fully saturate the body with stem cells while targeting specific areas of injury.
How are stem cells administered back into Alzheimer’s patients through TruStem Cell Therapy?
Alzheimer’s patients who receive stem cell therapy through us can receive multiple systemic and targeted administration methods:
Systemic IV infusion of their stem cells to fully saturate the entire body.
intranasal administration to target areas of damage in the central nervous system
What is unique about receiving stem cell therapy through TruStem Cell Therapy™ for Alzheimer’s disease?
Our focus is safety, efficacy, and patient-centric care when providing access to superior stem cell therapy.
We utilize only board certified surgeons, physicians and accredited clinicians to provide care for patients.
Laboratory protocols are developed and refined by our PhD Neuroscientist.
A clinical team with expertise in practicing cellularbased medicine.
Accredited Surgical Centers for enhanced procedural and patient safety
Targeted administration methods that direct stem cells toward specific
areas of injury which include the joints, brain, spine, lungs, etc…
Skilled Patient Advocates who are trained to provide truthful, realistic expectations resulting from stem cell therapy. We do not make outlandish promises of cures or inaccurate claims related to improvement rates.
Can this treatment cure Alzheimer’s Disease?
It is important for patients and caregivers to understand that current therapies, including stem cell treatment, does not provide a cure for Alzheimer’s disease. However, TruStem cell therapy does have the potential to improve a patient’s quality of life by reducing symptoms and complications related to Alzheimer’s disease as well as slowing its progression.
Are stem cells FDA approved for Alzheimer’s Disease?
The FDA has not approved stem cell therapy for Alzheimer’s disease. As noted above, studies have demonstrated the safety and efficacy of stem cell therapy for this condition but additional studies are needed before FDA approval can be secured.
What type of improvements can I expect from stem cell therapy?
It is possible through these treatments, to improve a patient’s quality of life by minimizing disease related symptoms and complications. For Alzheimer’s patients, it is possible to see improvements in any one or multiple disease related complications such as: cognitive decline, irritability, speech issues, fatigue, etc… If you have questions regarding how these treatments may help you, please contact one of our Patient Advocates to learn more.
How long will it take to see improvements?
It is difficult to predict the timeline of a patient’s response. Every patient responds differently to treatment. It could take weeks to months for the stem cells to provide noticeable results.
What type of side-effects can a patient expect from stem cell therapy?
Typically patients will experience some level of soreness and bruising lasting roughly a week as a result of the bone marrow harvesting procedure. Additional complications have not been observed. Over a hundred studies and clinical trials have demonstrated the safety and minimal side-effect profile of stem cell therapy.