TruStem Cell Therapy™
for Wound Healing

Symptoms/Complications of Chronic Wounds

Persistent pain
High risk of infections
Gangrene
Amputations

If you’ve experienced any of these conditions, please contact us.

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What type of stem cells are used and why?

TruStem Cell Therapy provides access to treatment that utilizes a patient’s stem cells isolated from their own bone marrow. Bone marrow contains several therapeutically useful cell types that are widely used or studied in regenerative medicine, transplantation, and immunotherapy. The main categories include:

1. Hematopoietic Stem Cells (HSCs)
Function: Generate all blood cells (red cells, white cells, platelets).

2. Mesenchymal Stem Cells (MSCs)
Multipotent cells that primarily function in tissue repair, regeneration and immunomodulation.

3. Endothelial Progenitor Cells (EPCs)
Help form and repair blood vessels which can promote angiogenesis, which can increase vasculature or blood flow.

4. Multipotent Adult Progenitor Cells (MAPCs)
Rare cells found in bone marrow which are capable of differentiating into multiple tissue types.

5. Multi-lineage-differentiating Stress-Enduring Cells(MUSE)
Stress-tolerant and pluripotent-like, meaning they can find damaged tissues, survive harsh environments, and differentiate into various cell types—such as nerve, muscle, or liver—without forming tumors

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What steps are involved in receiving treatment through TruStem Cell TherapyTM?

Step 1: Harvesting Your Bone Marrow

First a blood draw is performed followed by a minimally invasive bone marrow harvest via the iliac crest. Approximately 100cc’s of a patient’s own bone marrow is harvested through a minimally invasive, bone marrow aspiration procedure. TruStem Cell Therapy utilizes a powered bone marrow access system combined with local anesthetic allowing for consistently larger specimen of cells, extremely low levels of pain/invasiveness reported by most patients, and higher levels of sterility.

Bone marrow aspirate is preferentially utilized because it is one of the richest, most accessible sources of stem cells in the human body and falls within the FDA guidelines of minimal manipulation.

Step 2: Activating Your Stem Cells

TruStem Cell Therapy uses a multi-step protocol to isolate and activate the harvested stem cells which consists of minimal manipulation.

Both the blood and bone marrow are immediately delivered to our dedicated, onsite laboratory staffed by our team of technicians. Once your sample is in the lab our advanced proprietary process isolates and excites regenerative cells and concentrates healing factors to hyper-physiological levels in order to facilitate the creation of a highly effective, injectable therapeutic.

When also treating a chronic wound a soft biomatrix is created and loaded with healing factors and regenerative cells in addition to the process above.

Step 3: Re­administering Your Stem Cells

Stem Cell Clinical Studies are evaluating multiple ways to administer BMSCs, including:

Intravenously – BMSCs are delivered via a vein for distribution throughout the body with the goal of remodulating the patient’s immune system.

Intranasally – BMSCs are delivered via the highly vascular pathway of the nose. This delivery pathway improves the likelihood that the re-administered stem cells are able to cross the blood-brain barrier, which normally prevents substances from entering the brain via the bloodstream. Note, too, that intranasal infusion is a non-invasive and safe delivery system, and has been shown to be effective in the delivery of a number of drugs, including steroids and insulin n 8, 9.

Direct site injections – BMSCs are delivered to sites that need repair, such as muscles or tendons.

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What is unique about receiving stem cell therapy through TruStem Cell Therapy for wound care?

  • Our focus is safety, efficacy, and patient-centric care when providing access to superior stem cell therapy.
  • We utilize only board-certified surgeons, physicians and accredited clinicians to provide care for patients.
  • Laboratory protocols are developed and refined by our PhD Neuroscientist.
  • A clinical team with expertise in practicing cellular ­based medicine.
  • Accredited Surgical Centers for enhanced procedural and patient safety
  • Targeted administration methods that direct stem cells toward specific areas of injury which include the joints, brain, spine, lungs, etc…
  • Skilled Patient Advocates who are trained to provide truthful, realistic expectations resulting from stem cell therapy.

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Can this treatment cure Chronic Wounds?

This treatment has the potential to facilitate the complete healing of chronic wounds but may not necessarily address underlying issues causing chronic wounds. Such issues should be addressed to prevent wound reoccurrence.

Are stem cells FDA approved for Chronic Wound Treatment?

The FDA has not approved stem cell therapy for chronic wound treatment. As noted above, studies have demonstrated the safety and efficacy of stem cell therapy for this condition but additional studies are needed before FDA approval can be secured.

How long will it take to see improvements?

It is difficult to predict the timeline of a patient’s response. Every patient responds differently to treatment. It could take weeks to months for the stem cells to provide noticeable results.

What type of side ­effects can a patient expect from stem cell therapy?

Typically patients will experience some level of soreness and bruising lasting roughly a week as a result of the bone marrow harvesting procedure. Additional complications have not been observed. Over a hundred studies and clinical trials have demonstrated the safety and minimal side-­effect profile of stem cell therapy.