TruStem Cell Therapy™
for Multiple Sclerosis
How are stem cells administered back into MS patients through TruStem Cell Therapy?
How are stem cells administered back into Multiple Sclerosis patients through TruStem
Cell Therapy?
• Intranasal administration to target the myelin sheath deterioration of the neurons.
• Systemic IV infusion of their stem cells to fully saturate the entire body with the
goal of remodulating the patient’s immune system.
• Spinal injection to target spinal involvement / lesions
• Bladder catheterization to improve incontinence in patients
• Localized injections into atrophied muscles
What type of stem cells are used and why?
TruStem Cell Therapy provides access to treatment that utilizes a patient’s stem cells isolated from their own bone marrow. Bone marrow contains several therapeutically useful cell types that are widely used or studied in regenerative medicine, transplantation, and immunotherapy. The main categories include:
1. Hematopoietic Stem Cells (HSCs)
Function: Generate all blood cells (red cells, white cells, platelets).
2. Mesenchymal Stem Cells (MSCs)
Multipotent cells that primarily function in tissue repair, regeneration and immunomodulation.
3. Endothelial Progenitor Cells (EPCs)
Help form and repair blood vessels which can promote angiogenesis, which can increase vasculature or blood flow.
4. Multipotent Adult Progenitor Cells (MAPCs)
Rare cells found in bone marrow which are capable of differentiating into multiple tissue types.
5. Multi-lineage-differentiating Stress-Enduring Cells(MUSE)
Stress-tolerant and pluripotent-like, meaning they can find damaged tissues, survive harsh environments, and differentiate into various cell types—such as nerve, muscle, or liver—without forming tumors
What steps are involved in receiving treatment through TruStem Cell TherapyTM?
Step 1: Harvesting Your Bone Marrow
First a blood draw is performed followed by a minimally invasive bone marrow harvest via the iliac crest. Approximately 100cc’s of a patient’s own bone marrow is harvested through a minimally invasive, bone marrow aspiration procedure. TruStem Cell Therapy utilizes a powered bone marrow access system combined with local anesthetic allowing for consistently larger specimen of cells, extremely low levels of pain/invasiveness reported by most patients, and higher levels of sterility.
Bone marrow aspirate is preferentially utilized because it is one of the richest, most accessible sources of stem cells in the human body and falls within the FDA guidelines of minimal manipulation.
Step 2: Activating Your Stem Cells
TruStem Cell Therapy uses a multi-step protocol to isolate and activate the harvested stem cells which consists of minimal manipulation.
Both the blood and bone marrow are immediately delivered to our dedicated, onsite laboratory staffed by our team of technicians. Once your sample is in the lab our advanced proprietary process isolates and excites regenerative cells and concentrates healing factors to hyper-physiological levels in order to facilitate the creation of a highly effective, injectable therapeutic.
When also treating a chronic wound a soft biomatrix is created and loaded with healing factors and regenerative cells in addition to the process above.
Step 3: Readministering Your Stem Cells
Intravenously – BMSCs are delivered via a vein for distribution throughout the body with the goal of remodulating the patient’s immune system.
Intranasally – BMSCs are delivered via the highly vascular pathway of the nose. This delivery pathway improves the likelihood that the re-administered stem cells are able to cross the blood-brain barrier, which normally prevents substances from entering the brain via the bloodstream. Note, too, that intranasal infusion is a non-invasive and safe delivery system, and has been shown to be effective in the delivery of a number of drugs, including steroids and insulin n 8, 9.
Direct site injections – BMSCs are delivered to sites that need repair, such as muscles or tendons.
How are stem cells administered back into Multiple Sclerosis patients through TruStem Cell Therapy?
Multiple Sclerosis patients who receive stem cell therapy through us can receive multiple systemic and targeted administration methods:
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Systemic IV infusion of their stem cells to fully saturate the entire body.
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Intranasal administration to target the myelin sheath of the neurons
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Bladder catheterization to improve incontinence in patients
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Localized injections into atrophied muscles
Find out if you’re a candidate for Multiple Sclerosis Stem Cell Therapy™
What is unique about receiving stem cell therapy through TruStem Cell Therapy for Multiple Sclerosis?
- Our focus is safety, efficacy, and patient-centric care when providing access to superior stem cell therapy.
- We utilize only board-certified surgeons, physicians and accredited clinicians to provide care for patients.
- Laboratory protocols are developed and refined by our PhD Neuroscientist.
- A clinical team with expertise in practicing cellular based medicine.
- Accredited Surgical Centers for enhanced procedural and patient safety
- Targeted administration methods that direct stem cells toward specific areas of injury which include the joints, brain, spine, lungs, etc…
- Skilled Patient Advocates who are trained to provide truthful, realistic expectations resulting from stem cell therapy.
Can this treatment cure Multiple Sclerosis?
It is important for patients and caregivers to understand that current therapies, including stem cell treatment, does not provide a cure for MS. However, TruStem Cell Therapy may have the potential to improve a patient’s quality of life by reducing symptoms and complications related to MS as well as slowing its progression.
Are stem cells FDA approved for Multiple Sclerosis?
The FDA has not approved stem cell therapy for MS. As noted above, studies have demonstrated the safety and efficacy of stem cell therapy for this condition additional studies are needed before FDA approval can be secured.
What type of improvements can I expect from stem cell therapy?
It may be possible through treatment, to improve a patient’s quality of life by minimizing disease related symptoms and complications. For MS patients, may be possible to see improvements in any one or multiple disease related complications such as: mobility, pain, fatigue, incontinence, visual issues, mood, etc… If you have questions regarding how these treatments may help you, please contact one of our Patient Advocates to learn more.
How long will it take to see improvements?
It is difficult to predict the timeline of a patient’s response. Every patient responds differently to treatment. It could take weeks to months for the stem cells to provide noticeable results.
What type of side effects can a patient expect from stem cell therapy?
Typically patients will experience some level of soreness and bruising lasting roughly a week as a result of the bone marrow harvesting procedure. Additional complications have not been observed. Over a hundred studies and clinical trials have demonstrated the safety and minimal side-effect profile of stem cell therapy.